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  • Title: Xanthine, hypoxanthine and muscle pain. Histochemical and biochemical observations.
    Author: Isaacs H, Heffron JJ, Berman L, Badenhorst M, Pickering A.
    Journal: S Afr Med J; 1975 Jun 21; 49(26):1035-8. PubMed ID: 125457.
    Abstract:
    A suspected case of xanthine oxidase deficiency has been further investigated. The patient complained of arthralgia and myalgia. Further studies included histochemical and ultramicroscopic analysis of muscle sarcoplasmic reticulum, and biochemical studies. High levels of xanthine and hypoxanthine were found, while uric acid was absent in the muscle extracts.
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