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Title: How many lethal alleles? Author: Halligan DL, Keightley PD. Journal: Trends Genet; 2003 Feb; 19(2):57-9. PubMed ID: 12547508. Abstract: Knowledge of the frequency of lethal mutant alleles in a population is important for our understanding of population genetics and evolution, and yet there have been few attempts to measure their number in wild populations. A new study has revealed unexpectedly low numbers of segregating lethal alleles in two species of fish. More experiments are needed, however, to know whether this result is general.[Abstract] [Full Text] [Related] [New Search]