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  • Title: Macrophage activation syndrome following initiation of etanercept in a child with systemic onset juvenile rheumatoid arthritis.
    Author: Ramanan AV, Schneider R.
    Journal: J Rheumatol; 2003 Feb; 30(2):401-3. PubMed ID: 12563702.
    Abstract:
    Systemic onset juvenile rheumatoid arthritis (JRA) accounts for 10-15% of all JRA. Macrophage activation syndrome (MAS), which can also be considered as secondary hemophagocytic lymphohistiocytosis, is a potentially life-threatening complication of systemic onset JRA. We describe a child with systemic onset JRA who developed MAS after initiation of etanercept therapy.
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