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  • Title: [Detection of Epstein-Barr virus DNA in fine needle aspiration specimen from cervical lymphnodes with polymerase chain reaction].
    Author: Lei ZX, Liu QR, Yuan P.
    Journal: Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2000 Oct; 14(10):454-5. PubMed ID: 12563716.
    Abstract:
    OBJECTIVE: For the diagnosis of occult nasopharyngeal carcinoma. METHOD: Epstein-Barr virus in 58 fine needle aspirations from cervical metastatic lymphnodes were detected with polymerase chain reaction. RESULT: The positive reaction was found in 28/35 metastatic carcinoma samples from middle or upside neck. Negative reaction was found in 3 lymphomas, 4 metastatic carcinomas in clavicular superior lymphnodes and 15/16 inflammatory diseases of cervical lymphnodes. The sensibility of this method for the diagnosis of nasopharyngeal carcinoma was 89.3%. The specificity was 86.7%. CONCLUSION: The detection of Epstein-Barr virus in metastatic carcinoma from cervical lymphnodes had some clinical values for the diagnosis of occult nasopharyngeal carcinoma.
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