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  • Title: [The application of a combined Xylose-lactose tolerance-test in children with suspected malabsorption (author's transl)].
    Author: Brügmann G, Niessen KH, Schmidt K, Höntzsch D.
    Journal: Monatsschr Kinderheilkd (1902); 1976 Feb; 124(2):54-8. PubMed ID: 1256451.
    Abstract:
    A combined xylose-lactose tolerance-test and a duodenal biopsy were performed in 68 children with suspected malabsorption-syndrome. The purpose of the present work was to assess the diagnostic value of xylose concentrations in blood at different times and to determine the additional discriminatory value to glucose levels. The contribution of the glucose rise to a calculated discriminant function is statistically significant but practically negligible and therefore does not justify its determination. A small-bowel biopsy is recommended if the concentration of xylose after 60 min is less than 26 mg/100 ml or the increment of xylose concentration above fasting level is 18 mg/100 ml or less.
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