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  • Title: Renal aquaporin water channels: from molecules to human disease.
    Author: Schrier RW, Cadnapaphornchai MA.
    Journal: Prog Biophys Mol Biol; 2003 Feb; 81(2):117-31. PubMed ID: 12565698.
    Abstract:
    Following the discovery of the aquaporin-1 water channel in 1991, molecular techniques have been developed to examine the roles of renal aquaporins-1, -2, -3, and -4 in disorders of water balance. This article reviews current knowledge regarding aquaporin function and dysfunction in water-losing and water-retaining states.
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