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  • Title: [Structural elucidation of a new tetrahydroxystilbene of Radix Polygoni Multiflori Preparata and study on its cardiovascular activity].
    Author: Chen WS, Liu WY, Yang GJ, Zhang WD, Chu ZY, Chen HS, Qiao CZ.
    Journal: Yao Xue Xue Bao; 2000 Dec; 35(12):906-8. PubMed ID: 12567912.
    Abstract:
    AIM: To investigate the cardiovascular active constituents of Radix Polygoni multiflori Preparata. METHODS: Compounds were isolated from the water soluble extract with column chromatography of Sephadex, ODS and HPLC. The compounds were identified on the basis of spectral analysis (IR, EI-MS, FAB-MS, 1HNMR, 13CNMR, 2D-NMR) and phytochemical properties. Its inhibitory effect on the proliferation of bovine vascular smooth muscle cells were bioassayed in vitro. RESULTS: One compound was isolated and identified as: 2,3,5,4'-tetrahydroxystilbene-2-O-(6"-O-alpha-D- glucopyranosyl)-beta-D-glucopyranoside. CONCLUSION: Compound I is a new compound with cardiovascular activity.
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