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  • Title: [Effect of total diterpene of Rabdosia macrocalyx on mice of normal and immunosuppression].
    Author: Wang J, Yang J.
    Journal: Zhong Yao Cai; 1999 Jul; 22(7):348-50. PubMed ID: 12571930.
    Abstract:
    OBJECTIVE: The regulatory effects of total diterpene of Rabdosia macrocalyx (Dunn) Hara on immune function were studied. METHODS: The experimental immunosuppressive mouse models were induced by injection of cyclophosphamide. RESULTS: The index of thymus gland and spleen in normal and immunosuppressive mice were increased significantly. So were the level of hemolysin in serum when 50 mg/kg total diterpene were given. Delayed hypersensivity were also enhanced at the same condition. But there didn't show any change in carbon clearance test. CONCLUSION: Total diterpene of Rabdosia macrocalyx (Dunn) Hara possesses obvious regulatory action on immune function in mice.
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