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  • Title: [Climbing-upward inhibition of Oncomelania hupensis by niclosamide combination].
    Author: Zhu D, Xie FX, Bao ZP, Zhu DB, Ni CH.
    Journal: Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi; 2001; 19(6):348-50. PubMed ID: 12572067.
    Abstract:
    OBJECTIVE: To develop a combination of molluscicide/insecticide with a good molluscicidal effect, especially an inhibitory effect on climbing-upward of Oncomelania hupensis. METHODS: Experiments on molluscicidal and snail-climbing inhibition effect of the combination of niclosamide and shachongding [(dimethylamine) trithacyclohexane hydrochloride] were conducted by immersion and spraying in laboratory. RESULTS: The combination of niclosamide (0.2 mg/L) and shachongding (0.1 mg/L) showed an inhibition of 92.67% of snails to climb up. There was no significant difference in molluscicidal effect between the combination (LC90 0.198 mg/L) and niclosamide alone (LC90 0.207 mg/L). CONCLUSION: The combination showed an effective inhibition on the climbing-upward of snails in water so as to improve the molluscicidal effect and reduce the cost of mollusciciding.
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