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  • Title: Leukoencephalopathy with patchy lesions, temporal cystic degeneration, and normal head size.
    Author: Sener RN.
    Journal: Comput Med Imaging Graph; 2003; 27(1):87-91. PubMed ID: 12573893.
    Abstract:
    A 5 yr old girl is reported with patchy white matter lesions, cystic degeneration of the temporal tips, normal cortex, and normal cerebellum, documented by FLAIR, and diffusion-weighted MRI. This condition differed from the entity megalencephalic leukoencephalopathy with cysts by lack of diffuse involvement of the white matter and cortical thinning, by presence of a normal head size, and existence of a non-progressive, severe clinical condition. Occurrence of cystic degeneration in the temporal tips distinguished the condition from other leukoencephalopathies. This leukoencephalopathy appears to be a new distinct entity.
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