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  • Title: Huge prosthetic mitral valve thrombus: use of serial transesophageal echocardiography guidance in resolution.
    Author: Ozdemir N, Kaymaz C, Ozkan M.
    Journal: J Heart Valve Dis; 2003 Jan; 12(1):48-51. PubMed ID: 12578335.
    Abstract:
    The case is presented of a 35-year-old woman with major thrombotic obstruction of a 29-mm St. Jude Medical mitral valve prosthesis. The thrombi were treated with successive intravenous fibrinolysis under transesophageal echocardiographic guidance, without complication. One large and obstructive thrombus with a long and mobile component, and other smaller and mobile thrombi were detected. These were gradually lysed after two successive administrations of streptokinase (1.5 x 10(6) units over 24 h), and one session of recombinant tissue type plasminogen inhibitor (100 mg over 6 h).
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