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  • Title: [Y-chromosome-specific microsatellite variation in Li ethnic groups of Hainan Island, China].
    Author: Li DN, Ying DJ, Ou CY, Chen L, Zhou ZJ, Fu SM.
    Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2003 Feb; 20(1):46-8. PubMed ID: 12579500.
    Abstract:
    OBJECTIVE: The study was conducted to reveal the distribution of genetic polymorphism of four Y chromosome specific short tandem repeat (Y-specific STR) loci in Li ethnic groups in Hainan Island, China. METHODS: Four tetranucleotide STR loci were simultaneously amplified with fluorescently labeled primers, and genotypes were determined with an automated DNA sequencer. RESULTS: Among 230 unrelated males, the alleles at the four Y-specific STR loci were composed of some complex repeat structure. 4,5,4,5 alleles were observed in loci DYS3891, DYS390, DYS391, DYS393 respectively. A set of human allele ladders for the typing of the four Y-specific STRs was obtained in Li ethnic population. Gene diversity index (D) and haplotype diversity data were estimated for the four Y-STRs. CONCLUSION: The preliminary study indicates a reference population for detecting male migration events and should be useful in population genetics and forensic applications.
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