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  • Title: [Electrochemical behavior of ofloxacin at Pt/GC ion implantation modified electrode and its application].
    Author: Qian YG, Lu YQ, Hu JB, Mao YN, Li QL.
    Journal: Yao Xue Xue Bao; 2001 Feb; 36(2):127-30. PubMed ID: 12579880.
    Abstract:
    AIM: To study the electrochemical behavior of ofloxacin at Pt/GC ion implantation modified electrode. METHODS: With Pt/GC ion implantation modified electrode as working electrode, the behavior of ofloxacin was studied by voltammetry in 0.40 mol.L-1 KCl solution. RESULTS: A sensitive reductive peak of ofloxacin was obtained by linear sweep voltammetry. The peak potential was -1.35 V (vs SCE). The peak current was proportional to the concentration of ofloxacin over the range of 1.0 x 10(-6)-3.0 x 10(-5) mol.L-1 with the detection limit of 5.0 x 10(-7) mol.L-1. The behavior of reduction wave was studied and applied to determination of ofloxacin in tablets. CONCLUSION: The reduction process was irreversible. The element composition, atomicity form and depth of distribution at the surface of Pt/GC electrode were determined by Auger electron spectroscopy (AES), X-ray photoelectron spectroscopy (XPS) and scanning electron microscope (SEM). The catalysis behavior and reaction mechanism at Pt/GC modified electrode was also studied.
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