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  • Title: Malignant pleomorphic adenoma (malignant mixed tumor) of the trachea: a case report and review of the literature.
    Author: Demirağ F, Topçu S, Kurul C, Memiş L, Altinok T.
    Journal: Eur Arch Otorhinolaryngol; 2003 Feb; 260(2):96-9. PubMed ID: 12582787.
    Abstract:
    A case of malignant mixed tumor of the trachea in a 56-year-old man is described. His tumor was removed by segmental tracheal resection, and end-to-end anastomosis was performed. Histologically, the tumor was characterized by a biphasic composition showing admixtures of epithelial elements in varying proportions; these were cytologically atypical with prominent mitotic figures. However, stromal elements were osteoid and mixoid with a benign appearance. The patient had no evidence of disease in the head and neck region and had no history of previous surgery for a salivary gland tumor. These findings were interpreted as indicative of malignant pleomorphic adenoma of the trachea.
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