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  • Title: [The study on the anti-oxidation effect of root of Mallotus apelta in the rat model of liver fibrosis].
    Author: Zhao J, Lü Z, Wang X, Zhang X.
    Journal: Zhong Yao Cai; 2002 Mar; 25(3):185-7. PubMed ID: 12583162.
    Abstract:
    OBJECTIVE: To investigate the effect of root of Mallotus apelta in treatment of liver fibrosis and the effect of anti-oxidation in the rat model of liver fibrosis. METHODS: A rat model of liver fibrosis was induced with 40% CCl4 in peanut oil. A series of items were detected, which include ALT, AST, MDA, NO and hydroxyproline in the blood or liver tissues. RESULTS: The level of ALT, MDA, NO in serum were significantly decreased, the level of hydroxyproline was declined too, while the formation of liver fibrosis was successfully ameliorated. CONCLUSION: The root of Mallotus apelta could retain the progression of liver fibrosis, having a capacity of anti-oxidation. And the latter might be the reason of the former function.
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