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Title: [Study on the scavenging action of polysaccharide of Usnea longissima to oxygen radical and its anti-lipi peroxidation effects]. Author: Bian X, Jin J, Ding D, Zhang H. Journal: Zhong Yao Cai; 2002 Mar; 25(3):188-9. PubMed ID: 12583163. Abstract: OBJECTIVE: To study the scavenging action of polysaccharide of Usnea longissima Ach. (PUS) to oxygen free radical and its inhibiting action on lipidperoxidation. METHODS: The scavenging action to superoxide anion free radical (O2-.) was tested by xanthine-xanthine oxidase system. The scavenging action on hydroxyl free racical (OH.) and anti-lipidperoxidation effects were tested by Fenton reaction. RESULTS: The scaverging action was represented by the content scavenging 50% of all the free radical(IC50). The IC50 for O2-. and OH. were 0.45 mg/ml and 1.57 mg/ml respectively. The lipidperoxidation induced by OH. was weakly inhibited by PUS. CONCLUSION: PUS can apparently scavenge oxygen free radical. But it can only weakly inhibit the lipid peroxidation of hepatocyte homogenate of mice which resulted form hydroxyl free radical.[Abstract] [Full Text] [Related] [New Search]