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  • Title: Evaluation of antiherpesvirus-1 and genotoxic activities of Helichrysum italicum extract.
    Author: Nostro A, Cannatelli MA, Marino A, Picerno I, Pizzimenti FC, Scoglio ME, Spataro P.
    Journal: New Microbiol; 2003 Jan; 26(1):125-8. PubMed ID: 12585233.
    Abstract:
    The antiherpes virus-1 and genotoxic activities of diethyl ether extract from flowering tops of Helichrysum italicum (Compositae) were investigated. The extract showed significant antiviral activity at concentrations ranging from 400 to 100 microg/ml. This activity was not due to cytotoxic effect of the extract since Vero cells exhibited altered morphology or growth characteristics indicative of cytotoxic effects at higher concentration (800 microg/ml). Moreover H. italicum extract showed no DNA-damaging activity at concentrations up to 2000 microg/disk.
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