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  • Title: The Bloom's syndrome helicase: keeping cancer at bay.
    Author: Mohaghegh P, Hickson ID.
    Journal: Biologist (London); 2003 Feb; 50(1):29-33. PubMed ID: 12586954.
    Abstract:
    Bloom's syndrome, a very rare inherited disorder, predisposes its sufferers to the full range of cancers that afflict humanity. This predisposition is rooted in just one defective gene on chromosome 15. It encodes the BLM helicase - an enzyme that ordinarily protects against DNA damage arising during replication.
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