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  • Title: [Type A and C viruses particles in murine lymphoma L 5178Y].
    Author: Tapia-Arizmendi G, Arellano-Blanco J, Gómez-Estrada H, Férnandez-Quintero P, González-Garza T, Ochoa-Diaz H, Antillon AT.
    Journal: Arch Invest Med (Mex); 1976; 7(1):9-16. PubMed ID: 1259510.
    Abstract:
    The presence of virus particles and their possible mechanism of excretion was studied in cells of murine lymphoma L 5178Y grown intraperitoneally. Malignant cells obtained from 10 mice bearing this lymphoma were studied with the electron microscope. In 96% of the cells 1 to 30 viroid particles (VP) type C (VP-C) clumped or isolated, averaging six per cell were observed. Isolated VP-C were commonly seen within endoplasmic reticulum or budding off from cell surface. Such a finding was regarded as the mechanism of excretion. However, with the present findings it is not possible to draw any conclusions upon the oncogenic nature of the virus particles described herein.
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