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  • Title: [Effect of 17beta-estradiol on haloperidol effects in Wistar rats].
    Author: Andreeva IuA, Kudrin VS, Raevskiĭ KS.
    Journal: Eksp Klin Farmakol; 2002; 65(6):10-3. PubMed ID: 12596525.
    Abstract:
    It is established that the haloperidol catalepsy is much less pronounced in Wistar females than in males. Estradiol (10 mg/kg, i.p.) decreased intensity of the haloperidol catalepsy, reduced the haloperidol-induced increase in the dopamine turnover, and decreased the level of dopamine metabolites in nucleus accumbens of both female and male test animals. However, these effects are also more pronounced in females.
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