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Title: [A quantitative analysis of peptidergic innervation in sinoatrial node in cases of sudden manhood death syndrome]. Author: Cheng JD, Chen YC, Hu BJ. Journal: Fa Yi Xue Za Zhi; 2002 May; 18(2):70, 73. PubMed ID: 12596590. Abstract: OBJECTIVE: To study the distribution and proportion of neuropeptide containing nervers in the sinus node in cases of sudden manhood death syndrome (SMDS) and to explore the mechanism of SMDS. METHODS: Immunohistochemical staining and quantitative analysis of neuropeptide Y (NPY) and vasoactive intestinal peptide(VIP) in the sinus node in 6 cases of SMDS and in 12 cases of non-cardiac death(control group) were achieved by LSAB method and computerized image system. RESULTS: As for NPY positive materials, VIP positive materials and the ratio of VIP/NPY in the sinus nodes, there were no significant difference between the control group and SMDS group. CONCLUSION: The mechanism of SMDS and the abnormality of autonomic nervous innervation in the sinoatrial nodes maybe incorrelation.[Abstract] [Full Text] [Related] [New Search]