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  • Title: Effects of IgY antibody on the development of Marek's disease.
    Author: Kermani-Arab V, Moll T, Cho BR, Davis WC, Lu YS.
    Journal: Avian Dis; 1976; 20(1):32-41. PubMed ID: 1259663.
    Abstract:
    The effects of passive immunization with immunoglobulin Y (IgY) on the pathogenesis of Marek's disease (MD) were examined in an experimental line of White Leghorn chickens highly susceptible to MD. Purified IgY with anti-MDV antibody activity, when injected into chicks, delayed the development of MDV viremia and lesions until 9 days postinoculation (PI) with Marek's disease virus (MDV). The blastogenic response of spleen cells to concanavallin-A was depressed at 6 days PI in the birds without passive immunization, whereas it was not totally depressed until 17 days in birds passively immunized with IgY anti-MDV antibody.
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