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  • Title: Substrate inhibition of L-cysteine alpha,beta-elimination reaction catalyzed by L-cystathionine gamma-lyase of Saccharomyces cerevisiae.
    Author: Yamagata S, Isaji M, Yamane T, Iwama T.
    Journal: Biosci Biotechnol Biochem; 2002 Dec; 66(12):2706-9. PubMed ID: 12596872.
    Abstract:
    The alpha,beta-elimination of L-cysteine catalyzed by Saccharomyces cerevisiae L-cystathionine gamma-lyase (EC 4.4.1.1) was inhibited by the substrate. The absorption spectrum of the holoenzyme in the presence of L-cysteine showed that the substrate inhibition observed in this reaction was due mainly to removal of the cofactor.
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