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  • Title: Malignant Sertoli cell tumor in the retained abdominal testis of a unilaterally cryptorchid horse.
    Author: Pratt SM, Stacy BA, Whitcomb MB, Vidal JD, De Cock HE, Wilson WD.
    Journal: J Am Vet Med Assoc; 2003 Feb 15; 222(4):486-90, 450. PubMed ID: 12597422.
    Abstract:
    A 13-year-old Morgan gelding was evaluated because of a mass in the caudal region of the abdomen. The horse had been presumed to be a gelding, but necropsy findings revealed a retained testis in the right retroperitoneal space. Histologically, the retained testis contained neoplastic cells; metastases were identified in the liver, spleen, lungs, and sublumbar lymph nodes. Immunohistochemical examination of the testis and metastatic tissues confirmed the diagnosis of malignant Sertoli cell tumor. Testicular neoplasms are infrequently reported in stallions. Seminomas are most commonly reported, whereas Sertoli cell tumors are considered to be rare. Typical biological behavior of Sertoli cell tumors in horses is unknown. To the authors' knowledge, there have been 2 reports of Sertoli cell tumors in horses; the tumors developed in descended testes, and 1 tumor was malignant.
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