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  • Title: Simplakidine A, a unique pyridinium alkaloid from the Caribbean sponge plakortis simplex.
    Author: Campagnuolo C, Fattorusso C, Fattorusso E, Ianaro A, Pisano B, Taglialatela-Scafati O.
    Journal: Org Lett; 2003 Mar 06; 5(5):673-6. PubMed ID: 12605487.
    Abstract:
    Simplakidine A, a unique 4-alkyl-substituted pyridiunium alkaloid, has been isolated from the Caribbean sponge Plakortis simplex. The stereostructure of simplakidine A has been determined using MS and NMR data, molecular mechanics, and an extension of the J-based configuration analysis. Data about the growth-inhibition activity of simplakidine A are reported.
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