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  • Title: Familial bilateral papillary cystadenoma of the epididymis: report of three cases in siblings.
    Author: Tsuda H, Fukushima S, Takahashi M, Hikosaka Y, Hayashi K.
    Journal: Cancer; 1976 Apr; 37(4):1831-9. PubMed ID: 1260690.
    Abstract:
    This paper describes an unusual, familial bilateral papillary cystadenoma of the epididymis found in three siblings. The histological characteristics of the tumor were: 1) papillary proliferation of clear cells, consisting of both tall columnar and round ovoid cells, in the efferent duct epithelium; and 2) cystic dilatation of the duct with colloidal material. The present cases were unique in two respects: 1) familial bilateral papillary cystadenomas probably associated with Lindau's disease have not been reported previously: and 2) electron microscopic observations suggested that the tumors originated from the efferent duct.
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