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  • Title: Subcutaneous mastectomy and fibrocystic disease of the breast.
    Author: Pennisi VR.
    Journal: Clin Plast Surg; 1976 Apr; 3(2):205-16. PubMed ID: 1261177.
    Abstract:
    There has been a considerable amount of data presented to implicate moderate to severe fibrocystic disease as a strong precursor of breast cancer. When a premenopausal woman with nodular breasts presents a biopsy examination characterized by sclerosing adenosis, intraductal hyperplasia and/or papillomatosis, microcystic disease, macrocystic disease, or lobular neoplasia, her malignant potential will be much greater than when these disease processes are absent. As a result, a prophylactic subcutaneous mastectomy is indicated and breast reconstruction with either an immediate or a delayed mammary prosthesis implantation should be performed.
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