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  • Title: Capofungin therapy for Aspergillus lung infection in a boy with chronic granulomatous disease.
    Author: Sallmann S, Heilmann A, Heinke F, Kerkmann ML, Schuppler M, Hahn G, Gahr M, Rösen-Wolff A, Roesler J.
    Journal: Pediatr Infect Dis J; 2003 Feb; 22(2):199-200. PubMed ID: 12613459.
    Abstract:
    Neutrophils of patients with chronic granulomatous disease (CGD) are profoundly defective in killing microorganisms. As in patients with chemotherapy-induced neutropenia, CGD patients are highly susceptible to life-threatening invasive Aspergillus infections, and conventional antimycotic treatment is not always successful. The new drug, caspofungin, was used to treat Aspergillus lung infection in one child with CGD.
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