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  • Title: Treatment of advanced carcinoma of the prostate with estramustine phosphate.
    Author: Fosså SD, Miller A.
    Journal: J Urol; 1976 Apr; 115(4):406-8. PubMed ID: 1263316.
    Abstract:
    Estramustine phosphate has been useful in the treatment of advanced carcinoma of the prostate. Objective remissions were obtained with this therapy in 6 of 17 patients (35 per cent). The results presented herein indicate that the clinical response is to a certain extent caused by an estrogen effect, which was clearly demonstrable in a previously untreated patient. A specific cytostatic effect of estramustine phosphate, which is not yet clearly explained, may be responsible for remissions in some patients who have become resistant to conventional hormonal treatment.
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