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  • Title: [Effects of various adsorbants on coagulation factors (author's transl)].
    Author: Soulier JP, Prou-Wartelle O.
    Journal: Nouv Rev Fr Hematol; 1975; 15(2):195-211. PubMed ID: 126430.
    Abstract:
    Adsorption of clotting factors by various adsorbants is studied (tricalcium phosphate, baryum sulfate or carbonate or citrate, calcium oxalate, aluminium hydroxyde and several silicate such as: kaolin, celite, bentonite, attapulgite, beidellite, asbestos). The main properties of each adsorbant are listed as well as several applications such as: selective adsorption of fibrinogen, separation between fibrinogen and factor VIII, separation of factor II from the other components of the prothrombin complex. Activation of factors XII and XI by the various silicates, as well as the activation of factor V by attapulgite are studied. Finally, the action of such adsorbants on the fibrinolytic system is summarized.
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