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  • Title: Novel carboranyl C-glycosides for the treatment of cancer by boron neutron capture therapy.
    Author: Tietze LF, Griesbach U, Schuberth I, Bothe U, Marra A, Dondoni A.
    Journal: Chemistry; 2003 Mar 17; 9(6):1296-302. PubMed ID: 12645018.
    Abstract:
    The synthesis of the novel unprotected carboranyl C-glycosides 2 and 20-24 starting from ethynyl C-glycosides 1, 5-8, 10, and 13 is described. The new compounds are highly water-soluble and display only a very low cytotoxicity, which makes them promising candidates for use in boron neutron capture therapy for the treatment of cancer.
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