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Title: [Metabolic interactions between glucose and fructose]. Author: Malaisse WJ. Journal: Bull Mem Acad R Med Belg; 2002; 157(7-9):349-52; discussion 352-3. PubMed ID: 12647375. Abstract: Fructose-1-phosphate, the product of fructose phosphorylation by fructokinase, favours glucose phosphorylation by glucokinase, at the intervention of a regulatory protein. Glucose confers to glucokinase positive cooperativity, towards fructose. These reciprocal effects are operative in hepatocytes and pancreatic islets. They could optimize their glucostatic function.[Abstract] [Full Text] [Related] [New Search]