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  • Title: [Differential diagnosis of congenital fibrosis of the liver and hepatoportal sclerosis].
    Author: Radzhabova NI, Mansurov KhKh, Mirodzhov GK.
    Journal: Klin Med (Mosk); 2003; 81(1):67-9. PubMed ID: 12650101.
    Abstract:
    The article deals with differential-diagnostic criteria of inborn liver fibrosis and hepatoportal sclerosis. Congenital liver fibrosis is inherited and manifests at young age. It is characterized by marked hepatomegaly with stony dense liver, moderate splenomegaly with hypersplenism and portal hypertension in high activity of alkaline phosphatase and 5-HT, renal affection. Fibrosis locates around the biliary ducts. Hepatoportal sclerosis manifests more frequently in the adults with moderate hepatomegaly, marked splenomegaly with hypersplenism and predominance of anemia, high portal hypertension. Fibrosis is moderate and locates around portal vein branches in which thrombi are found.
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