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  • Title: Angiography in the diagnosis and therapy of frostbite.
    Author: Gralino BJ, Porter JM, Rosch J.
    Journal: Radiology; 1976 May; 119(2):301-5. PubMed ID: 1265260.
    Abstract:
    Five patients with frostbite injury were studied by selective angiography and treated by selective intra-arterial application of reserpine with follow-up angiography two days later. Control angiograms showed various degrees of vascular spasm as well as organic stenosis and occlusion. Intra-arterial reserpine produced dramatic subsiding of vasospasm, as evidenced by angiography and relief of clinical symptoms. Complete healing without tissue loss occurred in 4 patients. Amputation was necessary in one case, due at least in part to pre-existing peripheral atherosclerotic disease. Selective angiography was found to contribute significantly to both the diagnosis and therapy of frostbite injury.
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