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  • Title: [A case of auto-immune hepatitis associated with primary Sjogren's syndrome].
    Author: Kwon YD, Lee HS, Park CH, Jeen YT, Chun HJ, Lee SW, Choi JH, Kim CD, Ryu HS, Hyun JH.
    Journal: Taehan Kan Hakhoe Chi; 2003 Mar; 9(1):25-30. PubMed ID: 12657826.
    Abstract:
    Auto-immune hepatitis is a chronic necroinflammatory liver disorder that is characterized by hypergammaglobulinemia, auto-antibodies in serum, and, on histological examination, the presence of periportal hepatitis. Although it can be associated with a number of other auto-immune diseases, Sjogren's syndrome is rarely associated with auto-immune hepatitis. We herein report an unusual case of auto-immune hepatitis associated with primary Sjogren's syndrome. A 39-year-old woman was admitted to our hospital due to jaundice. Laboratory data showed negative viral hepatitis marker, increased serum IgG level, positive anti- nuclear antibody, and an increased rheumatoid factor titer. The patient had no history of taking medications and alcohol. Based on characteristic clinical features, liver biopsy findings, positive Schirmer's test, and salivary scintigraph, she was diagnosed as having auto-immune hepatitis and Sjogren's syndrome. The patient achieved complete remission with steroid monotherapy.
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