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  • Title: Primary heterologous carcinosarcoma of the ureter with necrotic malignant polyps. Report of a case and review of the literature.
    Author: Johnin K, Kadowaki T, Kushima M, Ushida H, Koizumi S, Okada Y.
    Journal: Urol Int; 2003; 70(3):232-5. PubMed ID: 12660464.
    Abstract:
    Carcinosarcoma is a rare and aggressive disease characterized by biphasic neoplasms with distinct mesenchymal and epithelial components. We report a case of ureteral carcinosarcoma with malignant necrotic polyps. The patient was a 58-year-old woman with painless hematuria, who was later diagnosed as having ureteral carcinosarcoma. Three long pendulous polypoid-shape tumors consisting of high-grade transitional cell carcinoma with chondrosarcomatous and osteosarcomatous elements were found. Two months after nephroureterectomy, the tumor relapsed in the bladder. Despite anterior exenteration, the patient died of local recurrence 6 months after her initial visit. To our knowledge, only 10 cases of this disease have been reported in the literature.
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