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Title: Leflunomide. Author: Cohen SB, Iqbal I. Journal: Int J Clin Pract; 2003 Mar; 57(2):115-20. PubMed ID: 12661795. Abstract: Leflunomide (Arava) was approved for the treatment of rheumatoid arthritis by the regulatory authorities in the US and Europe in 1998. This approval was based on three pivotal randomised clinical trials conducted in the US and Europe. This report will focus on the use of leflunomide in rheumatoid arthritis based on the data from these trials as well information on the efficacy and safety learned from post release clinical experience.[Abstract] [Full Text] [Related] [New Search]