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  • Title: Debulking for in-stent restenosis in the brachytherapy era: does it still have a role?
    Author: Tuli A, Subramaniyam V, Bakir S, Block PC, Crocker IR.
    Journal: J Invasive Cardiol; 2003 Apr; 15(4):209-12. PubMed ID: 12668849.
    Abstract:
    Despite the advent of intracoronary brachytherapy, treatment of in-stent restenosis, particularly diffuse in-stent restenosis, remains problematic. Adjunctive debulking prior to brachytherapy may improve long-term outcomes. We review the literature and report our results of a series of patients treated with excimer laser coronary atherectomy along with balloon angioplasty and brachytherapy for in-stent restenosis. We conclude that adjunctive debulking may improve the long-term clinical outcomes of patients with diffuse in-stent restenosis treated with angioplasty and intracoronary radiation. A randomized controlled trial is warranted.
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