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  • Title: [Lymphomatoid papulosis type C or transition to CD30+-T-cell lymphoma? A difficult differential diagnosis].
    Author: Plettenberg H, Neumann NJ, Ruzicka T, Megahed M.
    Journal: Hautarzt; 2003 Apr; 54(4):366-8. PubMed ID: 12669213.
    Abstract:
    Lymphomatoid papulosis (LyP) is a recurrent papulonodular eruption, characterized by self-healing skin lesions. While this disorder usually has a benign course, about 10% of the patients develop lymphoproliferative disorders such as CD30+ T cell lymphoma. We report 2 patients with LyP type C. In one case progress to a cutaneous CD30+ large T cell lymphoma could not be excluded. Histologic differentiation between LyP and malignant lymphoma causes considerable problems. In this regard, the evaluation of the clinical course is essential. A long-term follow-up including diagnostic imaging studies is required.
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