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  • Title: A comparison of familial and sporadic migraine in a headache clinic population.
    Author: Rainero I, Valfrè W, Gentile S, Lo Giudice R, Ferrero M, Savi L, Pinessi L.
    Journal: Funct Neurol; 2002; 17(4):193-7. PubMed ID: 12675262.
    Abstract:
    We compared the clinical, psychological and pharmacological characteristics of patients with familial migraine and patients with sporadic migraine. Five hundred and thirty consecutive new patients attending our Headache Center over a two-year period were involved in the study. The patients were divided into two groups: A. Familial migraine (famM)--at least one first-degree relative affected; B. Sporadic migraine (spoM)--no first-degree relative affected. Four hundred and twenty-four patients (80%) fulfilled the criteria for famM and 106 (20%) for spoM. The patients with famM showed a significantly (p<0.01) earlier age at onset of the disease. No significant difference in all the remaining features examined was found. Our data suggest that famM and spoM represent a single disease entity.
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