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  • Title: The effect of simultaneous administration of levarterenol and phentolamine on renal blood flow.
    Author: Cimmino VM, Bove EL, Argenta LC, Brown JW, Kirsh MM.
    Journal: Ann Thorac Surg; 1976 Feb; 21(2):158-63. PubMed ID: 1267912.
    Abstract:
    The effect of simultaneous administration of levarterenol and phentolamine upon renal blood flow was studied over a 3-hour period in 22 mongrel dogs. The infusion of levarterenol alone produced a fall in renal blood flow that ranged from 28 to 58% from the baseline value. When both drugs were administered simultaneously, renal flow fell only 17 to 22% from baseline (p less than 0.05). From these studies we conclude that the simultaneous administration of levarterenol and phentolamine in optimal ratios maintains renal blood flow near baseline levels.
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