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  • Title: Synthesis and cytotoxic evaluation of novel thiazolocarbazoles.
    Author: Lamazzi C, Chabane H, Thiery V, Pierre A, Leonce S, Pfeiffer B, Renard P, Guillaumet G, Besson T.
    Journal: J Enzyme Inhib Med Chem; 2002 Dec; 17(6):397-401. PubMed ID: 12683675.
    Abstract:
    Novel thiazolocarbazole derivatives 4 and 5 have been synthesized via the corresponding imino-1,2,3-dithiazoles 3. In vitro antitumor activity of these polyheterocyclic compounds was studied and the results show that 2-cyano derivatives exhibit a medium in vitro antiproliferative effect.
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