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  • Title: [Effects of flavonoids from semen Cuscutae on changes of beta-EP in hypothalamuses and FSH and LH in anterior pituitaries in female rats exposed to psychologic stress].
    Author: Wang J, Wang M, Ou Y, Wu Q.
    Journal: Zhong Yao Cai; 2002 Dec; 25(12):886-8. PubMed ID: 12685350.
    Abstract:
    OBJECTIVE: To study the mechanism of flavonoids from Semen Cuscutae (FSC) improving the ovarian endocrine functions. METHODS: (1) FSC were obtained from the semen of Cuscuta chinensis through solvent extraction and polyamide columnar chromatography. (2) Sound, light and electricity were combined into a stressful stimulas to induce psychologic stress in female rats. (3) To observe the effects of FSC on the changes of beta-EP in hypothalamuses, FSH and LH in anterior pituitaries and the changes in pituitary morphology in female rats exposed to psychologic stress. RESULTS: FSC decreased the content of beta-EP in hypothalamuses, and increased the numbers of basophilic cell and content of LH in anterior pituitaries, didn't change content of FSH in anterior pituitaries in female rats exposed to psychologic stress. CONCLUSION: FSC decreases the contents of beta-EP in hypothalamuses and increases contents of LH in anterior pituitaries in female rats exposed to psychologic stress, which may be one of the mechanism of FSC improving hypothalamus-pituitary-ovary axis.
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