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  • Title: [Clinical course of alcoholic pancreatitis].
    Author: Sadokov VM.
    Journal: Ter Arkh; 2003; 75(2):45-8. PubMed ID: 12685391.
    Abstract:
    AIM: To study a natural course of alcoholic pancreatitis (AP). MATERIAL AND METHODS: Follow-up clinical, laboratory and radiation examinations were made of 170 patients with alcoholic pancreatitis. Exocrine secretion of the pancreas was assessed by secretin-pancreozymin test. Morphological signs of pancreatitis were studied in patients who had died of pancreatic cancer. RESULTS: In 24% of patients AP manifested with acute attack. In 76% it was preceded with weak clinical symptoms. AP ran was complicated with pseudotumorous pancreatitis, calcinosis and pancreatic pseudocysts. Pancreatic secretion was suppressed in 87% patients though clinically it was evident only in 12% cases. Autopsy cases of pancreatic cancer carried morphological markers of chronic pancreatitis. CONCLUSION: Various clinical forms of AP represent stages of its development: early symptoms, recurrences, complications and decompensated failure of the pancreatic function. The presence of pancreatitis in patients with pancreatic cancer causes difficulties in differential diagnosis between these diseases.
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