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  • Title: Metachronous Wilms tumor associated with pulmonary embolism: how can we detect these cases early? A case report and literature review.
    Author: Ahmed R, al-Salti W, Raafat F, Morland B.
    Journal: Pediatr Hematol Oncol; 2003; 20(1):55-63. PubMed ID: 12687754.
    Abstract:
    A 4-year-old girl developed right metachronous Wilms tumor 2 years after completing treatment for a left-sided stage I Wilms tumor. The original treatment included 7 weeks of chemotherapy, delayed nephrectomy, and another 3 weeks of chemotherapy. The metachronous tumor on the right side extended into the inferior vena cava and right atrium. She developed pulmonary embolism as a result. She received chemotherapy and developed liquifaction of the tumor and toxic shock. She also had surgery. The patient is alive 3 years after the original diagnosis and 10 months after the relapse. The authors report this unusual case and discuss whether these cases can be identified early.
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