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  • Title: Lysosomal enzyme levels in human amniotic fluid cells in tissue culture. IV. %A N-acetyl-beta-D-glucosaminidase.
    Author: Butterworth J, Sutherland GR, Guy GJ, Bowser-Riley S, Bain AD.
    Journal: Clin Genet; 1976 May; 9(5):505-7. PubMed ID: 1269172.
    Abstract:
    Total and % A hexosaminidase were similar for primary cultures and later passages of amniotic fluid cells. The culture variables-through serial passage, within a passage and replicate primary cultures-resulted in some variation in total hexosaminidase, but an insignificant change in % A hexosaminidase. They are unlikely to give rise to any problems in the antenatal diagnosis of Sandhoff's and Tay-Sachs diseases.
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