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  • Title: [Churg-Strauss syndrome with alveolar hemorrhage].
    Author: Matsushima H, Takayanagi N, Ubukata M, Tokunaga D, Sato N, Kurashima K, Yanagisawa T, Sugita Y, Hoshi E, Kawabata Y, Kanazawa M.
    Journal: Nihon Kokyuki Gakkai Zasshi; 2003 Jan; 41(1):25-9. PubMed ID: 12693001.
    Abstract:
    A 35 year-old man was admitted to our hospital because of cough, wheezing, and paresthesia of the right upper extremity. He demonstrated marked eosinophilia, bronchial asthma, and mononeuritis multiplex. We diagnosed Churg-Strauss syndrome. Serum MPO-ANCA was elevated to 189 U/ml. Chest high-resolution computed tomography showed panlobular ground-glass attenuation in both lungs. BALF showed bloody fluid, and TBLB revealed findings consistent with eosinophilic pneumonia. Lung biopsy by VATS revealed eosinophilic pneumonia, pulmonary vasculitis, capillaritis, and hemosiderosis. The patient recovered after treatment with prednisolone and cyclophosphamide. We concluded that alveolar hemorrhage due to pulmonary capillaritis could be a complication in cases of Churg-Strauss syndrome.
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