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  • Title: [Histomorphological changes in the lymphoid and internal organs of adult guinea pigs in anaphylactic shock, induced 8 months after thymectomy].
    Author: Markov D, Kozarov I.
    Journal: Eksp Med Morfol; 1976; 15(1):18-23. PubMed ID: 1269459.
    Abstract:
    Anaphylactic shock was induced in adult guinea pigs eight months after operative thymectomy. It was established that thymectomy caused depletion of lymphoid tissue with atrophy of lymphyc follicles and disappearence of germinative centers in the spleen, mesenterial lymph gland and intestinal lymph tissue. There was no anaphyactic shock in 81.2% of the thymectomized animals as a result of the inhibited immunoallergic reactivity, but dystrophic and inflammatory changes in their parenchymatous organs were more frequent and graver in comparison with the nonthymectomized animals.
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