These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Nucleic acid base pair dynamics: the impact of sequence and structure using free-energy calculations.
    Author: Giudice E, Lavery R.
    Journal: J Am Chem Soc; 2003 Apr 30; 125(17):4998-9. PubMed ID: 12708848.
    Abstract:
    Molecular dynamics free-energy calculations of base pair opening within double helical DNA and RNA are used to explain why A-tracts (oligo-adenine repeats) greatly increase the lifetimes of AT base pairs, whereas the structural and the chemical changes involved in passing from B-DNA to A-RNA have comparatively small effects.
    [Abstract] [Full Text] [Related] [New Search]