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  • Title: Midazolam syrup as a premedication to reduce the discomfort associated with pediatric intravenous catheter insertion.
    Author: McErlean M, Bartfield JM, Karunakar TA, Whitman MC, Turley DM.
    Journal: J Pediatr; 2003 Apr; 142(4):429-30. PubMed ID: 12712062.
    Abstract:
    This randomized, double-blind, placebo-controlled study evaluated midazolam syrup for reducing discomfort from intravenous placement in children 9 months to 6 years. Parents and observers rated the child's discomfort by using visual analogue scales. Median parents' pain scores were significantly lower in the midazolam than the placebo group (P =.002). Midazolam effectively reduces discomfort associated with intravenous insertion.
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